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The prognostic impact of hexaminolevulinate-based bladder tumor resection in patients with primary non-muscle invasive bladder cancer treated with radical cystectomy

World Journal of Urology May 01, 2019

Renninger M, et al. - In this retrospective study involving 131 patients, researchers ascertained if outcomes of patients with primary non-muscle-invasive bladder cancer (NMIBC) who were eventually treated with radical cystectomy (RC) were affected by hexaminolevulinate-based (HAL) bladder tumor resection (TURBT). According to results, HAL-TURBT was related to a higher number of TURBTs before RC and administration of intravesical chemotherapy. Findings suggested that NMIBC resection under HAL has a beneficial effect on the outcomes of patients who will have to undergo RC during their disease course. This outcome may be due to improved risk stratification as the HAL resection may allow for timely and adequate treatment of more patients.

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