Mahieua R, Dubée V, Seegers D, et al. - In order to assess the optimal treatment of streptococcal prosthetic joint infections (PJIs), researchers retrospectively reviewed a cohort of 70 streptococcal PJIs in seven reference centers for the management of complex bone and joint infections, covering the period January 1, 2010, to December 31, 2012. Infections of total hip arthroplasty were reported in 47 patients and infections of total knee arthroplasty were reported in 23 patients. They noted a high risk of relapse in correlation with the treatment of prosthetic joint infections (PJIs) due to Streptococcus agalactiae. Poor prognosis was noted in correlation with the conservative approach with debridement and implant retention. The success rate was higher in correlation with debridement, antibiotics and implant retention (DAIR) with polyethylene exchange. In selected patients, the one-stage exchange strategy led to an excellent cure rate. For PJIs with streptococcal species, the superiority of no antimicrobial treatment was established.