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The Pringle maneuver reduces the infusion rate of rocuronium required to maintain surgical muscle relaxation during hepatectomy

Journal of Anesthesia May 09, 2018

Kajiura A, et al. - Researchers determined the continuous infusion rates of rocuronium necessary to obtain the surgical muscle relaxation before, during, and after the Pringle maneuver on patients who underwent hepatectomy. In patients who received total intravenous anesthesia with propofol, intubation with rocuronium was started after obtaining the calibration of acceleromyography. The infusion rate was adjusted every 15 min so that the first twitch height (% T1) might become from 3 to 10% of control. Regulating rocuronium administration using muscle relaxant monitoring was considered essential in order to deal with the decrease in muscle relaxant requirement by the Pringle maneuver in case of continuous administration of rocuronium during surgery performing the Pringle maneuver.
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