Hao R, Saleh M, Liang T, et al. - Researchers sought to determine prevalence of Serious Bacterial Infections (SBI) in healthy children with febrile neutropenia, via this systematic review and meta-analysis. PubMed, EMBASE, and Web of Science were explored to identify studies with patients exhibiting Absolute Neutrophil Count < 1000 cells/mm ³ up to 18 years of age visiting emergency department with a main problem of fever (temperature > 38.0C) and who had a workup for SBI. They found 2,066 citations of which 5 studies (1,693 patients) met the inclusion criteria. A broad range of the SBI prevalence of 1.9% (<0.01% - 11%) resulted from spectrum bias in every study. Based on findings, febrile healthy neutropenic and non-neutropenic children have a similar risk for SBI, if the clinical suspicion is low.