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The prevalence of hypercapnia during acute infection in children on chronic noninvasive ventilation: A retrospective study

Pediatric Pulmonology May 15, 2020

Beyltjens T, de Leede SR, van Eekelen I, et al. - Children on chronic ventilatory support were examined for the prevalence of hypercapnia during an acute admission. Researchers conducted a retrospective study of 43 children aged 0 to 18 years who routinely used bilevel positive airway pressure or continuous positive airway pressure at home, and who were diagnosed with an acute infection, and were hospitalized at the pediatrics department or pediatric intensive care unit. They recorded capillary blood gas analysis and parameters of the built‐in software of the home ventilator. As per findings, hypercapnia is prevalent in, nearly, a quarter of the cases of chronic home ventilation during an acute infection. Findings thereby justify a prospective study on the monitoring of respiratory rate in cases with chronic respiratory insufficiency as an indicator for hospitalizations with hypercapnia; Further, they emphasize using volume guarantee mode of ventilation to limit hypercapnia.

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