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The postprandial-to-fasting serum C-peptide ratio is a predictor of response to basal insulin-supported oral antidiabetic drug(s) therapy: A retrospective analysis

Diabetes Therapy Mar 26, 2018

Mu PW, et al. - The intention of the authors was to gauge the factors predicting patient response to basal insulin-supported oral antidiabetic drug therapy (BOT) for the treatment of type 2 diabetes mellitus (T2DM). It was disclosed that responders had a shorter duration of diabetes and a higher 2-h postprandial C-peptide-to-fasting C-peptide ratio (2 h-PCP/FCP). Hence, the inference drawn was that a higher 2 h-PCP/FCP ratio and a lack of previous insulin treatment raised the likelihood of BOT success.
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