Tojo N, et al. - In a single-facility retrospective study, researchers sought to compare the effectiveness of trabectome surgery for patients with differing preoperative intraocular pressure (IOP) values. They assessed surgical outcomes based on three grades of preoperative IOP: high (hi-IOP, > 26 mmHg), middle (mid-IOP, 18– 26 mmHg), and low (lo-IOP, < 18 mmHg). Cases of 204 eyes that underwent trabectome surgery were studied and followed for > 2 years. Trabectome surgeries substantially lowered IOP values from 23.0 ±  7.2 mmHg to 13.6 ±  3.6 mmHg at 2 years post-surgery. It was difficult for patients with preoperative IOP < 18 mmHg to reduce their IOP > 20% with trabectome surgery. Additional glaucoma surgery is also needed in patients with preoperative IOP values of > 26 mmHg.