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The novel ultrasonographic marker of uterocervical angle for prediction of spontaneous preterm birth in singleton and twin pregnancies: A systematic review and meta-analysis

Fetal Diagnosis and Therapy Feb 11, 2021

Hessami K, Kasraeian M, Sepúlveda-Martínez Á, et al. - Researchers sought to evaluate the evidence on the uterocervical angle (UCA) predictive role in spontaneous preterm birth (sPTB) by performing a systematic review and meta-analysis. They systematically searched PubMed, Web of Science, Scopus, and Google scholar from inception up to June 2020, and identified 11 articles reporting second-trimester UCA of 5,061 pregnancies for inclusion in this study. Per findings, a wider ultrasound-measured UCA in the second trimester appears to be linked with the raised risk of sPTB in both singleton and twin pregnancies, which strengthens the clinical evidence that UCA has potential utility as a predictive marker of sPTB.

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