De Santis A, et al. – This study aims to verify if the modification of portal pressure induced by a transjugular intrahepatic portosystemic shunt (TIPS) parallels the modification of spleen or liver stiffness measured by acoustic radiation force impulse (ARFI) in order to understand if ARFI may be used to monitor the modification of portal pressure in patients with cirrhosis. In detecting the modification of portal pressure induced by TIPS, spleen stiffness is superior to liver stiffness. In order to monitor the modification of portal hypertension, this makes spleen stiffness a potential non invasive method. To establish applicability and clinical utility of this promising tool in the treatment of portal hypertension, further studies are required.