The lectin pathway and coagulation in lung cancer patients undergoing lobectomy – A randomised controlled trial
Thrombosis Research Apr 04, 2018
Larsen JB, et al. - Lectin pathway proteins were studied during lung cancer surgery. The impact of low molecular weight heparin (LMWH) on lectin pathway proteins and the associations between lectin pathway proteins and coagulation in lung cancer patients undergoing video-assisted thoracoscopic surgery lobectomy were determined. For all proteins, except mannose-binding lectin (MBL)-associated serine protease (MASP)-1, the concentrations decreased during surgery in both groups. The findings did not reveal any association between lectin pathway proteins and coagulation, with the exception of M-ficolin and fibrinogen. In contrast with LMWH, lectin pathway proteins were affected by surgery. The lectin pathway proteins and coagulation did not present with any consistent connection.
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