Albayati Z, et al. – Analysts undertook this study to probe the influence of cytomegalovirus (CMV) on the expression of HLA–G and its ligand KIR2DL4 by human peripheral blood leucocyte subsets. Together with a significant decrease in CD56dimCD16+ NK cells, following stimulation with IL–2, an increase in the proportion of CD56+ T cells positive for KIR2DL4 was found. These outcomes demonstrated that CMV impacted HLA–G expression in healthy subjects and appeared to contribute to viral immune evasion.