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The influence of anemia on clinical outcomes in venous thromboembolism: Results from GARFIELD-VTE

Thrombosis Research May 28, 2021

Goto S, Turpie AGG, Farjat AE, et al. - In this study, baseline characteristics, treatment patterns, and 24-month outcomes were compared in patients with and without anemia within GARFIELD-VTE. Researchers designed a global, prospective, non-interventional registry of real-world treatment practices (GARFIELD-VTE). For analysis, 7,698 were eligible out of the 10,679 patients enrolled in GARFIELD-VTE. Poisson regression was used to calculate event rates and 95% confidence intervals. Cox proportional hazard models were applied to estimate adjusted hazard ratios. It was shown that venous thromboembolism (VTE) patients with concomitant anemia have a higher risk of adverse clinical outcomes in comparison with those without anemia. There is a need for further optimization of anticoagulation therapy for VTE patients with anemia.

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