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The incidence of oral anticoagulant interruption among stroke patients with atrial fibrillation and subsequent stroke

European Journal of Neurology Feb 26, 2020

Kim JM, Park KY, Yu IW, et al. - Researchers examined a cohort of Korean stroke patients with atrial fibrillation for the incidence and causes of oral anticoagulant (OAC) cessation, and subsequent stroke after OAC withdrawal. In Korean Atrial Fibrillation Evaluation Registry in Ischemic Stroke patients (K-ATTENTION), a multicenter cohort study, stroke registries from 11 tertiary centers in Korea are merged. They assessed 3,213 stroke patients with atrial fibrillation; of these, 229 patients were reported to have a total of 329 episodes of OAC interruption after index stroke (mean age = 72.9 ± 8.3 years, 113 female patients). This suggests that a substantial number of stroke patients with atrial fibrillation had been through temporary interruption of OAC following index stroke, which was linked with stroke recurrence of 4.0 cases per 100 interruption episodes.
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