Rayner LH, et al. - Using a representative UK primary care database (894,646 adults), researchers determined the incidence of asthma in subjects with type 2 diabetes (T2DM), as well as the relation to metformin, sulphonylureas, and insulin therapy. They matched 29,217 pairs of T2DM patients and controls via 1:1 propensity score matching. Compared with matched controls, asthma development was less likely to occur among subjects with T2DM. Overall, findings were suggestive of a possible protective impact of T2DM against asthma development. An increased risk of asthma was observed in relation to insulin use, while a reduced risk was observed in relation to the use of metformin and sulphonylureas in those with T2DM.