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The impact of occupational activities during pregnancy on pregnancy outcomes: A systematic review and meta-analysis

American Journal of Obstetrics and Gynecology Sep 30, 2019

Cai C, Vandermeer B, Nerenberg K, et al. - Researchers investigated how occupational activities during pregnancy influence maternal and fetal health outcomes. Searching five electronic databases and three gray literature sources up to March 15, 2019, they included 80 observational studies (N = 853,149).They gained ‘low’ to ‘very low’ certainty evidence indicating an increased odds ratio (OR) of miscarriage (OR: 1.31), and preeclampsia (OR: 1.35) in correlation with lifting objects ≥ 11 kg. Increased odds of preterm delivery (OR: 1.31) and having a low-birth-weight neonate (OR: 2.08) were observed in correlation with lifting objects for a combined weight of > 100kg per day. Increased odds of preterm delivery (OR: 1.11), and having a small-for-gestational-age neonate (OR: 1.17) were evident in correlation with prolonged standing. A heavy physical workload was correlated with raised odds of preterm delivery (OR: 1.23), and having a low-birth-weight neonate (OR: 1.79). These observations suggest a correlation of physically demanding work during pregnancy with an increased risk of adverse pregnancy outcomes.
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