The impact of modifiable risk factors on the long-term outcomes of non-alcoholic fatty liver disease
Alimentary Pharmacology and Therapeutics Dec 07, 2019
Paik JM, et al. - Given the development of 7 cardiovascular (CV) health metrics (poor, intermediate and ideal health) by the American Heart Association to improve CV health, researchers sought to determine population-attributable fractions of CV health metrics to all-cause and CV mortality among patients with non-alcoholic fatty liver disease (NAFLD). From the National Health and Nutrition Examination Survey (NHANES 1988-1994), they included 4,040 adults with NAFLD and 7,515 without. Following median follow-up of 19.2 years, the death of 1,136 NAFLD individuals (327 CV deaths) and 1,600 non-NAFLD individuals (447 CV deaths) was reported. Lower risk for all-cause and CV mortality was noted with the attainment of the increased number of ideal health metrics. They estimated that 66% of all-cause deaths and 83% of CV deaths were preventable in case all NAFLD individuals achieved 7 ideal health metrics. Lack of glycaemic control and hypertension were the largest mortality contributors among NAFLD individuals.
Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free or login with your existing account.
4 reasons why Doctors love M3 India
-
Exclusive Write-ups & Webinars by KOLs
-
Daily Quiz by specialty
-
Paid Market Research Surveys
-
Case discussions, News & Journals' summaries