Todorova MG, et al. - Researchers conducted the study for analyzing the effect of macular edema on microvascular and metabolic alterations in retinitis pigmentosa (RP). Optical coherence tomography angiography (OCTA) and retinal oximetry (RO) were conducted on 94 eyes: 64 eyes diagnosed with RP with (ME-RP) and without (no-ME-RP) macular edema were compared with 30 control eyes. The author’s perception of inherited retinal diseases is improved by a combined microvascular structure-metabolic function approach. The more altered microvascular-metabolic function seems to be the result of the involvement of macular edema in RP. Thus, when assessing microvascular and/or metabolic changes in RP, macular edema should be taken into account.