McClelland ML, Sesoko CS, MacDonald DA, et al. - Researchers conducted the study for analyzing the immediate physiological effects on heart rate, breathing frequency, blood pressure, blood sugar, SpO2, pulmonary function, and oral temperature following e-cigarette use and secondhand vapor exposure. This study included 149 volunteers; 76 vaped mint-flavored e-cigarettes with 5% nicotine for 20 minutes while seated next to 73 nonvaping subjects who agreed to be exposed to the vapor. Vaping for 20 minutes with mint-flavored e-cigarettes containing 5% nicotine resulted in significant immediate physiological changes. Exposure to e-cigarette vapor increased oral temperature significantly in the same amount of time. Vaping or vapor exposure had no effect on blood sugar or FVC levels.