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The high expression of FOXA1 is correlated with a favourable prognosis in salivary duct carcinomas: A study of 142 cases

Histopathology Jul 17, 2018

Urano M, et al. - Researchers assessed the clinicopathological implications of forkhead-box protein A1 (FOXA1) in salivary duct carcinoma (SDC) as well as biomarker status and clinical outcome. For this investigation, 142 SDCs were involved. Results revealed that SDCs with a higher FOXA1 labelling index was correlated with longer overall survival and progression-free survival. The study findings suggested that FOXA1 might biologically interact with the androgen receptor and PI3K signaling pathways in SDC and could be a biomarker correlated with a favorable prognosis.

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