Dwijayanti F, et al. - Researchers focused on the 5-year survival rate among patients having nasopharyngeal cancer (NPC) depending on tumor response and their prognostic factors following the receipt of neoadjuvant chemotherapy, followed by chemoradiation. They retrospectively examined records of 261 patients between January 2009 and December 2013. Cases with metastasis were removed from the study. For patients showing complete response (CR), partial response (PR), and progressive disease (PD), the estimated tumor response rates were 33.7, 45.2, and 21.2%, respectively. By tumor response, 5-year survival rates among CR, PR, and PD patients were estimated to be 71.0, 30.4, and 10.6%, respectively. Tumor response, educational background, job, alcohol consumption, clinical stage, and prompt treatment were all identified as significant independent prognostic factors. The CR group vs the PR and PD groups demonstrated a higher survival likelihood of patients with NPC receiving neoadjuvant chemotherapy, followed by chemoradiation. This corroborates that improved patient survival can be achieved by early detection. To know about the factors impacting tumor response in NPC, long-term follow-up is needed.