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The fibrin glue application enhances surgical success rate in endonasal endoscopic dacryocystorhinostomy with lacrimal sac preservation

ENT Journal Oct 28, 2019

Ceylan SM, Erdoğan C, Sozen T, et al. - In patients undergoing endoscopic endonasal dacryocystorhinostomy, researchers compared lacrimal sac flap preserving techniques with or without fibrin glue. Between February 2011 and March 2016, 132 patients who had unilateral endonasal dacryocystorhinostomy were included. Study participants were divided into two groups: the nonfibrin glue group (n = 66) and fibrin glue anastomosis group (n = 66). In the fibrin glue anastomosis group, the rate of surgical success, defined as the patients’ subjective report of epiphora relief and objective endoscopic confirmation of ostium patency verified by a positive functional dye test, was significantly higher than in the nonfibrin glue group. In the nonfibrin glue group, the complication rate was 6.1%, while in the fibrin glue anastomosis group it was 4.5%. In both groups, the complication rate was comparable. According to this retrospective study, the development of an anastomosis between lacrimal sac flaps and nasal mucosa using fibrin glue improves the endonasal endoscopic dacryocystorhinostomy outcome.
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