Hu ZZ, et al. - In this retrospective cohort study involving 278 patients, researchers explored nasal natural killer/T-cell lymphoma (NKTL) clinical characteristics in patients with prominent ocular symptoms and those with general nasal NKTL to improve the early diagnosis of nasal NKTL. There were no significant differences between patients with general nasal NKTL and patients with nasal NKTL and prominent ocular symptoms in gender and age distribution. The early diagnosis of patients with prominent ocular symptoms is difficult and easy to misdiagnose vs patients with general nasal NKTL. Patients with nasal NKTL and prominent ocular symptoms mostly present with advanced disease stages, and most patients have B symptoms and a high positive rate of EBV DNA. Patients with nasal NKTL and prominent ocular symptoms mostly have advanced stages of the disease, and most patients have B symptoms and a high rate of EBV DNA positive.