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The NRP1 migraine risk variant shows evidence of association with menstrual migraine

The Journal of Headache and Pain Apr 22, 2018

Pollock CE, et al. - Researchers explored whether single nucleotide polymorphisms (SNPs) strongly linked with migraine were individually or collectively related to menstrual migraine (MM). Genotyping via the Agena MassARRAY platform was used on DNA samples from 235 women diagnosed with menstrual migraine as per International Classification for Headache Disorders II (ICHD-II) criteria and 140 controls. According to the data, NRP1 could be significant in the etiology of MM. Some genetic commonality was reported between common migraine subtypes (migraine without aura and migraine with aura) and MM. Identifying associated SNPs could be the starting point to an improved comprehension of how genetic factors could contribute to the menstrual migraine sub-type.

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