Kang J, Zhao Z, Lv J, et al. - A meta-analysis was conducted to evaluate the effectiveness and safety of gabapentin following total knee arthroplasty (TKA) and total hip arthroplasty (THA). Researchers comprehensively retrieved electronic databases including PubMed, EMBASE, Cochrane Central Register of Controlled Trials, MEDLINE, and ClinicalTrials.gov for randomized controlled trials from their inception to June 2019. This analysis enrolled a sum of 7 studies, which compared the administration of gabapentin with that of placebo for the treatment of postoperative pain, in our meta-analysis. The meta-analysis demonstrated that gabapentin did not reduce postoperative pain, cumulative morphine consumption, and the incidence of adverse effects after TKA and THA. After TKA and THA, there was not enough data to guide the administrations of gabapentin for postoperative pain.