Xing X, Chen L, Xu Z, et al. - Since there is a lack of robust evidence on the efficacy of topical tranexamic acid (TA) on melasma in the Chinese population, researchers sought to assess the effectiveness and safety of 1.8% liposomal TA and microneedling with 5% TA solution on melasma. To receive 1.8% liposomal TA twice daily, microneedling with 5% TA solution weekly or 2% hydroquinone every night, 60 melasma patients were recruited and randomized. The authors concluded that 1.8% liposomal TA and microneedling with 5% TA solution are both safe and effective for melasma.