Ozkan AS, et al. - In this prospective study, researchers determined the links between secondhand smoke (SHS) exposure and oxygenation during one-lung ventilation (OLV) in lobectomy surgery and between SHS exposure and postoperative analgesic consumption. Participants included 60 adult patients with American Society of Anesthesiologists score II to III, aged 18 to 65 years, with a body mass index (BMI) <35 kg/m² scheduled for lobectomy surgery by open thoracotomy. Findings demonstrated that significantly lower arterial oxygen pressure was detected during OLV in patients exposed to SHS vs nonsmokers. SHS-exposed patients had significantly increased arterial carbon dioxide values. In patients exposed to SHS vs in nonsmokers, increased morphine consumption for postoperative analgesia was reported.