Abbasi F, Pourjalali H, Zargarzadeh N, et al. - A hypothesis was generated that chronic inflammation is related to the development of breast cancer. In breast cancer patients, exercise training led to significant decrease in CRP level, which was more considerable following concurrent aerobic and resistance training and in long-term intervention.

• This is a systematic review and meta-analysis of 18 studies that assessed the impact of exercise training on inflammatory biomarkers in adult women with breast cancer.

• A significant reduction in CRP (WMD: −0.55; 95% CI: −1.10, −0.01) but no significant alterations in serum levels of TNF-α, IL-6, IL-8, IL-10, INF-ɣ, IL-1β were evident post-exercise training.

• Subgroup analyses showed that best outcomes were reached in long-term intervention and following concurrent training.