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The effects of anesthesia induction and positive pressure ventilation on right-ventricular function: An echocardiography-based prospective observational study

BMC Anesthesiology Nov 15, 2019

Magunia H, et al. – Via performing a prospective observational study, researchers evaluated how two- and three-dimensional echocardiography-derived parameters of right ventricle function may be affected by anesthesia induction (using midazolam, sufentanil and rocuronium, followed by sevoflurane) with positive pressure ventilation (PEEP 5, tidal volume 6–8 mL/kg) among 53 patients undergoing elective cardiac surgery. Prior to and immediately post-anesthesia induction, they performed transthoracic echocardiography exams and recorded those combined with hemodynamic parameters and ventilator settings. Findings revealed that following anesthesia induction and initiation of positive pressure ventilation, the right ventricular ejection fraction and right ventricular stroke volume were preserved. However, a significant decline in the baso-apical right ventricular function was evident.

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