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The effect of universal infant vaccination on the prevalence of hepatitis B immunity in adult solid organ transplant candidates

Journal of Viral Hepatitis Oct 20, 2020

Koc OM, Kuypers D, Dupont LJ, et al. - Given the recommendation of hepatitis B virus (HBV) immunity to optimize outcomes after solid organ transplantation (SOT), researchers here examined the prevalence and factors predictive of HBV immunity at the time patients were placed on transplant waiting list over a period from 1997 to 2019 in a low HBV endemic region. From the University Hospitals Leuven transplant database, they included data of 3,297 SOT candidates in this study. Renal transplant candidates were noted to have superior HBV immunity rate (55.3%), and for liver, cardiac and pulmonary transplant candidates, this number was 21.5%, 15.4% and 16.8%, respectively. Over the 20‐year period, HBV immunity has increased in relation to the introduction of universal infant HBV vaccination. Nevertheless, there was a low overall HBV immunity at the time of listing for organ transplantation, suggesting the necessity for an increased awareness and vaccination strategy at an early disease stage.

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