The effect of rocuronium on ventilatory leak and sealing pressure using a supraglottic airway device: A randomized clinical trial
Acta Anaesthesiologica Scandinavica May 09, 2020
Fujimoto M, et al. - Since there is a lack of clarity regarding the transition of ventilatory leak and sealing pressure in supraglottic airway devices following administration of neuromuscular blocking agents, so researchers investigated whether ventilatory leak would reduce because of the rise in sealing pressure following administration of 0.15 and 0.30 mg/kg rocuronium iv. The random allocation of 40 patients to a control group or one of two rocuronium groups was done. Following general anaesthesia induction, experts inserted an i‐gel prior to rocuronium delivery. Immediately, measurements of ventilatory leak and sealing pressure were obtained. Then, experts administered 0.15 mg/kg or 0.30 mg/kg rocuronium iv and once more measured ventilatory leak and sealing pressure. They collected measurements in the control group just following the insertion of the supraglottic airway device and 5 minutes later, with no use of any additional drug. According to the findings, ventilatory leak with a supraglottic airway device reduced independently of neuromuscular blockade, although a reduction in sealing pressure may potentially be induced by the neuromuscular blockade.
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