Cohen J, et al. - This systematic review strived to determine the impact of right colon retroflexion on improving adenoma detection compared with conventional colonoscopy without retroflexion, as well as determine the rates of retroflexion maneuver success and adverse events. Compared with conventional colonoscopy, colonoscopy with right-sided retroflexion significantly increased the detection of adenomas in the right colon with a high rate of maneuver success and a small risk of adverse events. Therefore, reexamination of the right colon in retroflexed view needed to be strongly considered in future standard of care colonoscopy guidelines for quality improvement in colon cancer prevention.