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The effect of renin-angiotensin system blockade on abdominal aortic aneurysm growth, rupture, and perioperative outcomes: A systematic review and meta-analysis

Journal of Vascular Surgery Evidence based | Sep 14, 2017

Salata K, et al. - Authors here summarized the literature regarding the effects of angiotensin-converting enzyme inhibitor (ACEi) and angiotensin receptor blocker (ARB) treatment on human abdominal aortic aneurysm (AAA) growth, rupture, and perioperative mortality. In this study, ACEi treatment deemed to have no effect on AAA growth or rupture rates. They recommend more prospective, long-term research to assess the effect of renin-angiotensin system blockade on AAA growth, rupture, and perioperative mortality.
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