Shibib KS, et al. - Experts aspired to investigate the effect of laser power, blood perfusion, thermal and optical properties of human liver tissue on thermal damage in laser-induced interstitial thermotherapy (LITT). They found that increasing laser power, absorption, and scattering coefficient increased the damage zone while increasing tissue water content, perfusion rate, and tissue anisotropy factor decreased the damage zone in this mathematical model for LITT. In the pre-estimation of the damage zone before starting the therapy, these findings served as important aspects for doctors, so as to kill only the desired zone.