Axtell AL, et al. - In view of the conflicting evidence regarding the prognosis of recipients of advanced age donor hearts, especially in young recipients, researchers undertook this retrospective analysis including 11,433 patients aged 18 to 45 who received a cardiac transplant from 2000 to 2017. Donors less than 45 years provided heart to overall 10,279 patients and donors greater than 45 to 1145 patients. They noted decreased long-term survival among young recipients of older donor hearts, however, reduction in this risk is noted in donors without atherosclerosis. They recommend carefully weighing the long-term hazard of this practice against the risk of waitlist mortality.