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The effect of coexisting autoimmune thyroiditis in children with type 1 diabetes on optical coherence tomography results

Pediatric Diabetes Mar 04, 2021

Wysocka‐Mincewicz M, Baszyńska‐Wilk M, Gołębiewska J, et al. - In this prospective, observational study, researchers sought to evaluate the impact of thyroid hormones status and coexistence of autoimmune thyroiditis on optical coherence tomography and optical coherence tomography angiography results in children with type 1 diabetes (T1D). A total of 175 children with T1D who were admitted to the hospital and signed informed consent to participate in the study were evaluated. The following parameters have been analyzed: fovea avascular zone, foveal thickness, parafoveal thickness (PFT), ganglion cell complex, loss volume (global‐GLV, focal‐FLV), capillary vessel density: superficial (whole‐wsVD, foveal‐fsVD, parafoveal‐psVD), and deep (whole‐wdVD, foveal‐fdVD, parafoveal‐pdVD. Significant correlations were detected between thyroid‐stimulating hormone level and PFT, psVD. The co-occurrence of T1D and AT worsens the status of the retinal parameters in the group of patients presented. More research is required to explore these relationships and their possible effects on the development of diabetic retinopathy.

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