Kim W, Jang H, Kim YT, et al. - In this community-based, cross-sectional study, researchers ascertained if glucose metabolic disorders due to body fatness are associated with regional changes in brain structure and a decline in neuropsychological function in cognitively healthy older adults. From 2016 to 2019, 429 candidates had their cortical thickness and subcortical volume measured using 3T magnetic resonance imaging, as well as their cognitive function measured using the neuropsychological screening battery. Using partial least square structural equation modelling, the impacts of body fatness mediated by impaired glucose metabolism on neuroimaging markers and cognitive function was examined. The findings show that impaired glucose metabolism caused by excess body fatness affects memory decline as well as regional grey matter atrophy in elderly people who do not have any neurological disease.