Fargotstein M, et al. – This analysis focused on the impact of antipsychotic medications on acoustic startle latency in schizophrenia (SCZ). The results of this study revealed that latency was partially normalized by antipsychotic medication, but this did not obscure the slower latency in SCZ compared to controls (CON). Therefore latency is both trait and state related, whereas medication normalized prepulse inhibition of the acoustic startle reflex (PPI) and obscured any difference between SCZ and CON.