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The effect of a basic skin care product on the structural strength of the dermo-epidermal junction: An exploratory, randomised, controlled split-body trial

International Wound Journal Jun 17, 2021

El Genedy-Kalyoncu M, Richter C, Surber C, et al. - An exploratory, randomized controlled clinical trial with a split-body design was carried out in 2018 at the Clinical Research Centre for Hair and Skin Science at the Charité-Universitätsmedizin Berlin, Germany, to explore the connection between a basic skin care intervention and the adhesion strength of the dermo-epidermal junction. A total of 18 participants were screened for eligibility and 17 healthy female individuals were involved. The authors conclude that topical application of basic skin care products can improve mechanical adhesion of the dermo-epidermal junction and that the parameter “time to blistering” is an appropriate outcome in clinical research to measure dermo-epidermal adhesion strength.

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