Fak M, et al. - Authors evaluated the changes taking place in the hydrolipid coat of the skin after microdermabrasion measured by skin hydration and sebum level. On the cheeks, a statistically significant difference in stratum corneum hydration was found 30 minutes after treatment and immediately after the procedure in the T-zone. Irrespective of skin type and face area, sebum reduction was seen immediately after the procedure. Also, 1 hour after the procedure, sebum value was found to return to baseline. For the clinical improvement following microdermabrasion, the observed changes in epidermal barrier function could be responsible.