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The diagnostic performance of MRI for detection of extramural venous invasion in colorectal cancer: A systematic review and meta-analysis of the literature

American Journal of Roentgenology Sep 02, 2019

Kim TH, et al. - Fourteen studies (n = 1,751 patients) were systematically reviewed and meta-analyzed by the researchers regarding the diagnostic test accuracy of MRI for identifying extramural venous invasion (EMVI) in patients with colorectal cancer (third most common cancer worldwide and the fourth leading cause of cancer death in the world). Pooled sensitivity and specificity was 0.61 and 0.87, respectively. According to the Cochran Q test and Higgins I2 heterogeneity index, substantial heterogeneity was noted. Publication bias was noted. Greater rates of advanced T category, use of high-resolution MRI, and use of antispasmodic drugs were exhibited to significantly impact heterogeneity. Location of the primary tumor, preoperative treatment status, study design, the definition of the reference standard, magnetic field strength, and use of functional MRI were not statistically notable. Thus, for the detection of EMVI in colorectal cancer, MRI explicates moderate sensitivity and good specificity. Moreover, the use of high-resolution MRI may enhance diagnostic performance.
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