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The Diabetes Unmet Need with basal insulin Evaluation (DUNE) study in type 2 diabetes: Achieving HbA1c targets with basal insulin in a real-world setting

Diabetes, Obesity and Metabolism Mar 21, 2019

Meneghini LF, et al. – Researchers reported on the achievement of physician-selected individualized HbA1c targets in people with type 2 diabetes, newly or recently initiated on basal insulin, in a real-world setting. In addition, they examined the association of hypoglycemia with target achievement. In this 12-week, prospective, single-arm, observational study, almost all 3,139 evaluable participants (99.7%) had been set individualized targets by their physicians, with over half of all participants having HbA1c targets between 7.0% and < 7.5%. Outcomes revealed no achievement of individualized HbA1c targets by most participants using basal insulin. HbA1c targets were achieved more frequently among participants who experienced symptomatic hypoglycemia.

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