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The developmental changes of retinal microvasculature in children: A quantitative analysis using OCT angiography

American Journal of Ophthalmology May 15, 2020

Li S, Yang X, Li M, et al. - Researchers conducted this prospective cross-sectional study to measure the macular microvasculature in healthy children of various ages utilizing optical coherence tomography angiography (OCTA). Participants in the study were 333 normal children aged from 4 to 16 years old. OCTA was conducted on a 3 X 3 mm area centered on the macular region. Macular vascular density and perfusion density both increased with age among the different age groups. In children, macular vascular density and perfusion density increases continuously with age. Despite the fact that the fovea avascular zone (FAZ) area and perimeter did not change, the FAZ microstructure was pruning and tending to form a smooth and regular avascular area during development.

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