Njuguna HJ, et al. – In this work, researchers piloted the use of a multi–pathogen respiratory Taqman Array Cards (TAC) to identify pathogens in respiratory samples collected from non–fatal and fatal cases and their matched asymptomatic controls. They identified similar rates of pathogen detection among cases and controls that made interpretation of results challenging. It seems that cycle threshold (Ct)–values might be helpful in interpreting clinical relevance of detected pathogens using multi–pathogen diagnostic tools.