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The comparison of two mealtime insulin dosing algorithms for high and low glycaemic index meals in adolescents with type 1 diabetes

Diabetic Medicine Nov 04, 2020

Erdal B, et al. - In this randomized, single‐blind and crossover trial, researchers contrasted the postprandial glycaemic effects of carbohydrate counting and food insulin index algorithms following the consumption of protein‐rich, high‐fat meals with different glycaemic index (GI) in adolescents with type 1 diabetes. The sample consisted of 15 adolescents aged 14‐18 years with type 1 diabetes. Participants consumed two separate test meals with identical energy, macronutrients, and food insulin index, but the nearly two-fold difference in GI, randomly on four consecutive mornings at home. The food insulin index algorithm significantly reduced peak glucose excursion, incremental area under the curve and coefficient variation of blood glucose in the high‐GI meal compared with carbohydrate counting, though there was no difference between two algorithms in the low‐GI meal. After the consumption of high‐GI meals in adolescents with type 1 diabetes, the food insulin index algorithm may be useful for postprandial glycaemic control.

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