Glyn-Owen K, Bohning D, Parkes J, et al. - A systematic review and meta‐analysis of cohort studies were conducted to evaluate the combined effect of alcohol and body mass index on the risk of chronic liver disease. Researchers carried out electronic searches of Ovid Medline, Embase Classic + Embase, until 17th June 2020 for cohort studies of adults without pre-existing liver disease. They used a Poisson regression log-linear model to investigate for statistical interaction between alcohol and BMI and to conduct a one-stage meta-analysis. In this analysis, searches distinguished 3,129 studies—16 were eligible. The analysis enrolled nine cohorts including a total of 1,121,514 participants. A significantly increased risk of chronic liver disease was found in participants who were both overweight/obese and consumed alcohol above the UK recommended limits. According to the results, this evidence should inform advice given to patients and risk stratification by healthcare professionals.