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The combination of endoluminal radiofrequency ablation and metal stent implantation for the treatment of malignant biliary stenosis – randomized study

European Journal of Radiology Jun 29, 2021

Andrasina T, Rohan T, Panek J, et al. - Researchers investigated if improved survival or stent patency could be conferred by endobiliary radiofrequency ablation prior metal stent insertion in malignant biliary stenosis. In this prospective, randomized study, there were 76 patients with histologically proven malignant biliary stenosis. Self-expandable metal stent insertion was received by 40 patients in the control arm. Patients in the experimental arm underwent endoluminal ablation with a bipolar radiofrequency catheter, conducted immediately prior to stent insertion. Experts identified no major complications associated with the stent insertion and the endoluminal ablation. An increased patency rate, only in patients with cholangiocarcinoma, was shown to be conferred by endobiliary radiofrequency ablation prior metal stent insertion, however, findings showed no improvement in survival.

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