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The clinicopathological significance of HES1 promoter hypomethylation in patients with colorectal cancer

OncoTargets and Therapy Dec 14, 2017

Wu Y, et al. - Researchers here determine the methylation status of the Hairy/enhancer of split 1 (HES1) promoter and correlations with clinicopathological parameters and prognosis in colorectal cancer (CRC). Based on the findings, they conclude that promoter hypomethylation upregulates HES1 expression and plays an important role in the progression and prognosis of CRC patients.
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