Zhao YR, et al. - As CCBE1 is expressed in various tumors and its expression correlates with lymphangiogenesis and angiogenesis, researchers sought the clinical significance of CCBE1 expression in colorectal cancer (CRC). For this purpose, they compared the CCBE1 expression in 30 pairs of fresh CRC tissues with adjacent normal (AN) tissues using quantitative real-time PCR (qRT-PCR), Western blotting and immunohistochemistry (IHC) staining. Outcomes revealed that high levels of CCBE1 in CRC contribute to its aggressiveness and a poor prognosis. This suggests the possible utility of CCBE1 as a novel potential biomarker to predict CRC patients’ prognosis.