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The clinical prognostic value of the neutrophil-to-lymphocyte ratio in brain metastases from non-small cell lung cancer-harboring EGFR mutations

Cancer Management and Research Jul 16, 2020

Li H, Wang W, Yang X, et al. - Researchers assessed the predictive values of pretreatment neutrophil-to-lymphocyte ratio (NLR) in brain metastasis (BM) from non–small cell lung cancer-with mutations in the epidermal growth factor receptor (EGFR) gene in this study with 133 of these patients. In both variable and multivariable analysis, longer survival was linked to an NLR value equal to or less than 2.99. Overall, in BMs from lung adenocarcinoma with EGFR mutations, NLR was identified as an independent prognostic factor. Experts suggested the likely utility of NLR as a prognostic biomarker as well as its appropriateness for inclusion in the clinical prognostic index specific to patients with BMs.

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