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The clinical impact of chronic liver disease in patients undergoing transcatheter and surgical aortic valve replacement: Systematic analysis of the 2011–2017 US hospital database

Catheterization and Cardiovascular Interventions Sep 30, 2021

Lee DU, Han J, Fan GH, et al. - Chronic liver disease (CLD) is linked to increased mortality and complications in patients receiving surgical aortic valve replacement (SAVR), while no linkage was seen in patients undergoing transcatheter aortic valve replacement (TAVR).

  • After matching for demographics and comorbidities, for TAVR, 606 and 1,818 were with or without CLD; for SAVR, 1,353 and 4,059 were with and without CLD.

  • There were no differences in mortality or length of stay after TAVR, while CLD-present patients had somewhat higher expenses.

  • In terms of complications, there were no changes.

  • There was no change in mortality in multivariate analysis.

  • CLD patients experienced increased mortality, length of stay, and expenses in SAVR.

  • Patients with CLD also had a higher rate of respiratory failure and bleeding. CLD exhibited a higher mortality rate in multivariate analysis.

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